HYPERMAG Publications

Below, you can browse the publications of current members of the HYPERMAG center.

If you are looking for a specific publication, publications from a specific researcher or former center members, we recommend that you search our group's profile at DTU's online research database ORBIT or HYPERMAG alumni.

 

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2020
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Cleaning of a fluid path system for hyperpolarization of a pharmaceutical product

Ardenkjær-Larsen, Jan Henrik
Patent no.: WO2020178310, Date: 2020-03-04

Type: Patent

Status: Published     |    Year: 2020

2018
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2016
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Hyperpolarized 1-13c-1,1-bis(acetoxy(methyl))-2,2'-cyclopropane as metabolic marker for mr

Lerche, Mathilde Hauge ; Jensen, Pernille Rose ; Karlsson, Magnus ; Napolitano, Roberta (Inventor) ; Cabella, Claudia (Inventor) ; Miragoli, Luigi (Inventor) ; Colombo Serra, Sonia (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: EP3016687, Date: 2015-01-08

Type: Patent

Status: Published     |    Year: 2016

2015
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Hyperpolarized 2-oxoglutarate as metabolic agent in mr

Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Cabella, Claudia (Inventor) ; Caminiti, Lara (Inventor) ; Colombo Serra, Sonia (Inventor) ; Miragoli, Luigi (Inventor) ; Poggi, Luisa (Inventor) ; Venturi , Luca (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: EP2911704, Date: 2015-09-02

Type: Patent

Status: Published     |    Year: 2015

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Hyperpolarized amino acids

Karlsson, Magnus ; Lerche, Mathilde Hauge ; Jensen, Pernille Rose
Patent no.: EP2833924, Date: 2015-02-11

Type: Patent

Status: Published     |    Year: 2015

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Hyperpolarized esters as metabolic markers in mr

Jensen, Pernille Rose ; Lerche, Mathilde Hauge ; Karlsson, Magnus ; Cabella, Claudia (Inventor) ; Colombo Serra, Sonia (Inventor) ; Miragoli, Luigi (Inventor) ; Venturi, Luca (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: EP2950826, Date: 2015-12-09

Type: Patent

Status: Published     |    Year: 2015

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Hyperpolarized media transport vessel

Skloss, Timothy William (Inventor) ; Murray, Jonathan Alan (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Cherukuri, Murali K. Cherukuri (Inventor) ; Bernardo, Marcelino (Inventor) ; Devasahayam, Nallathamby (Inventor)
Patent no.: US2015091573, Date: 2015-04-02

Type: Patent

Status: Published     |    Year: 2015

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Intra-operative cancer diagnosis based on a hyperpolarized marker

Lerche, Mathilde Hauge ; Karlsson, Magnus ; Jensen, Pernille Rose
Patent no.: EP2847591, Date: 2015-03-18

Type: Patent

Status: Published     |    Year: 2015

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Triarylmethyl radicals.

Karlsson, Magnus ; Napolitano, Roberta (Inventor) ; Visigalli , Massimo (Inventor) ; Lerche, Mathilde Hauge ; Jensen, Pernille Rose ; Tedoldi, Fabio (Inventor)
Patent no.: EP2872520, Date: 2015-05-20

Type: Patent

Status: Published     |    Year: 2015

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Waveguide volume probe for magnetic resonance imaging and spectroscopy

Zhurbenko, Vitaliy
Patent no.: WO2015063067, Date:

Type: Patent

Status: Published     |    Year: 2015

2014
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Method and apparatus to hyperpolarize materials for enhanced mr techniques

Urbahn, John A. (Inventor) ; Leach Arthur, Michael (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Ernst Stautner , Wolfgang (Inventor)
Patent no.: US2014123681, Date: 2014-05-08

Type: Patent

Status: Published     |    Year: 2014

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Process for the preparation of hyperpolarized derivatives for use in mri analysis

Aime, Silvio (Inventor) ; Battista Giovenzana, Giovanni (Inventor) ; Tedoldi, Fabio (Inventor) ; Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Colombo Serra, Sonia (Inventor)
Patent no.: EP2766050, Date: 2014-08-20

Type: Patent

Status: Published     |    Year: 2014

2013
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Composition comprising acetic anhydride and a gadolinium complex, and method for the use in hyperpolarisation mri analysis.

Lerche, Mathilde Hauge ; Karlsson, Magnus ; Jensen, Pernille Rose ; Colombo Serra, Sonia (Inventor) ; Visigalli, Massimo (Inventor) ; Aime, Silvio (Inventor) ; Tedoldi, Fabio (Inventor)
Patent no.: WO2013083535, Date: 2013-06-13

Type: Patent

Status: Published     |    Year: 2013

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Fluid path system for dissolution and transport of a hyperpolarized material

Urbahn, John Arthur (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Leach, Andrew Michael (Inventor) ; Telfeyan, Eric John (Inventor) ; Dietrich, David Key (Inventor) ; Whitt, David Brandon (Inventor) ; Miller, Peter (Inventor) ; Stautner, Ernst Wolfgang (Inventor)
Patent no.: EP20130150859, Date: 2013-07-17

Type: Patent

Status: Published     |    Year: 2013

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Folded waveguide resonator

Zhurbenko, Vitaliy
Patent no.: WO2013139656, Date: 2012-03-20

Type: Patent

Status: Published     |    Year: 2013

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Process for preparing hyperpolarized substrates and method for mri

Aime, Silvio (Inventor) ; Battista Giovenzana, Giovanni (Inventor) ; Tedoldi, Fabio (Inventor) ; Maiocchi, Alessandro (Inventor) ; Uggeri, Fulvio (Inventor) ; Jensen, Pernille Rose ; Karlsson, Magnus ; Lerche, Mathilde Hauge ; Visigalli , Massimo (Inventor) ; Crosetti, Marco (Inventor) ; Poggi, Luisa (Inventor)
Patent no.: EP2555803, Date: 2013-02-13

Type: Patent

Status: Published     |    Year: 2013

2011
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Electron spin resonance imaging scanner

Ardenkjær-Larsen, Jan Henrik ; Murray, Jonathan Alan (Inventor) ; Robb, Fraser John Laing (Inventor) ; Hurd, Ralph Eugene (Inventor) ; Taracila, Victor (Inventor)
Patent no.: WO2011137203, Date: 2011-11-03

Type: Patent

Status: Published     |    Year: 2011

 

Method for the production of hyperpolarized 129Xe

Ardenkjær-Larsen, Jan Henrik ; Hansson, Lennart (Inventor) ; Johannesson, Haukur (Inventor) ; Servin, Rolf (Inventor) ; Wistrand, Lars-Goran (Inventor)
Patent no.: US8003077, Date:

Type: Patent

Status: Published     |    Year: 2011

2010
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Mr imaging agent or medium compressing hzperpolarised 13c alanine and methods of imaging wherein such an imaging medium is used.

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Månsson, Sven (Inventor) ; In't Zandt , Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: EP2237801, Date: 2010-10-13

Type: Patent

Status: Published     |    Year: 2010

2009
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Apparatus and method for a fully automated preparation of a hyperpolarizing imaging agent

Al-Khalidy, Abdul Rahman Abdallah (Inventor) ; Campbell, Bruce (Inventor) ; Urbahn, John Arthur (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Staudinger, Vincent Paul (Inventor) ; Roy , Jaydeep (Inventor)
Patent no.: US7633290, Date: 2010-03-25

Type: Patent

Status: Published     |    Year: 2009

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Composition and method for generating a metabolic profile using 13c-mr detection

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt , Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009077575, Date: 2009-06-25

Type: Patent

Status: Published     |    Year: 2009

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Dnp polariser and method of producing a hyperpolarised selected material

Ardenkjær-Larsen, Jan Henrik ; Wolber, Jan (Inventor) ; Johannesson, Haukur (Inventor) ; Meyer, Werner (Inventor) ; Reicherz, Gerhard (Inventor) ; Heckmann, Jörg (Inventor)
Patent no.: WO2009150211, Date: 2009-12-17

Type: Patent

Status: Published     |    Year: 2009

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Imaging medium comprising hyperpolarised 13c-acetate and use thereof

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt, Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009027388, Date: 2009-03-05

Type: Patent

Status: Published     |    Year: 2009

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Imaging medium comprising hyperpolarised 13 c-lactate and use thereof.

Lerche, Mathilde Hauge ; Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; MAANSSON,, SVEN (Inventor) ; Zandt, Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose
Patent no.: WO2009013350, Date: 2009-01-29

Type: Patent

Status: Published     |    Year: 2009

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Method of Cardiac Imaging

Lerche, Mathilde Hauge ; Zandt, Rene (Inventor) ; Golman, Klaes (Inventor) ; Thanning, Mikkel (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Petersson, Stefan (Inventor)
Patent no.: US2009162287, Date: 2009-06-25

Type: Patent

Status: Published     |    Year: 2009

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Method to produce hyperpolarised amino acids and aminosulphonic acids

Lerche, Mathilde Hauge ; Karlsson, Magnus ; Jensen, Pernille Rose
Patent no.: WO2009098191, Date: 2009-08-13

Type: Patent

Status: Published     |    Year: 2009

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Mr imaging agent, imaging medium and methods of imaging wherein such an imaging medium is used

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt , Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009080739, Date: 2009-07-02

Type: Patent

Status: Published     |    Year: 2009

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Mr imaging agent or medium compressing hyperpolarised 13c alanine and methods of imaging wherein such an imaging medium is used.

Gisselsson, Anna (Inventor) ; Hansson, Georg (Inventor) ; Maansson, Sven (Inventor) ; Zandt, Rene (Inventor) ; Karlsson, Magnus ; Jensen, Pernille Rose ; Lerche, Mathilde Hauge
Patent no.: WO2009098192, Date: 2009-08-13

Type: Patent

Status: Published     |    Year: 2009

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Nozzle for a polarizer for dynamic nuclear polarization (DNP)

Ardenkjær-Larsen, Jan Henrik ; Dietrich, David Key (Inventor) ; Andreas Gram , Karl (Inventor) ; Leach, Andrew M. (Inventor) ; Miller, Peter (Inventor) ; Telfeyan, Eric J. (Inventor) ; Thanning, Mikkel (Inventor) ; Whitt, David B. (Inventor)
Patent no.: WO2009027422, Date: 2016-07-08

Type: Patent

Status: Published     |    Year: 2009

2008
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Apparatus and method for fully automated closed system quality control of a substance

Miller, Peter (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Bradney, Martin John (Inventor) ; Leach, Andrew Michael (Inventor) ; Sontum, Per Christian (Inventor) ; Telfeyan , Eric John (Inventor) ; Whitt, David Brandon (Inventor) ; Wolber, Jan (Inventor)
Patent no.: US2008275659, Date: 2009-04-14

Type: Patent

Status: Published     |    Year: 2008

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Fluid path system for dissolution and transport of a hyperpolarized material

Urbahn, John A. (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Leach, Andrew Michael (Inventor)
Patent no.: GB2448054, Date: 2008-10-01

Type: Patent

Status: Published     |    Year: 2008

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Method to produce hyperpolarised carboxylates and sulphonates in the presence of inorganic cations.

Lerche, Mathilde Hauge ; Karlsson, Magnus
Patent no.: EP1998813, Date: 2007-03-21

Type: Patent

Status: Published     |    Year: 2008

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Sorption pump with integrated thermal switch

Urbahn, John A. (Inventor) ; Ardenkjær-Larsen, Jan Henrik
Patent no.: WO2008115615, Date: 2008-09-25

Type: Patent

Status: Published     |    Year: 2008

2007
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Method and apparatus to hyperpolarize materials for enhanced mr techniques

Urban, John A. (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Stautner, Ernst W. (Inventor) ; Amm, Bruce C. (Inventor) ; Feenan, Peter J. (Inventor) ; Mangano, Roy A. (Inventor) ; Reeves, David G. (Inventor)
Patent no.: WO2008121458, Date: 2008-10-09

Type: Patent

Status: Published     |    Year: 2007

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Method of cardiac imaging with the use of hyperpolarized 13c-pyruvate

Lerche, Mathilde Hauge ; Zandt, Rene (Inventor) ; Golman, Klaes (Inventor) ; Thanning, Mikkel (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Peterson, Stefan (Inventor)
Patent no.: EP1824523, Date: 2007-08-29

Type: Patent

Status: Published     |    Year: 2007

2006
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Method of producing a composition, composition and its use

Thaning, Mikkel (Inventor) ; in't Zandt, Rene (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Wolber, J. (Inventor) ; Lerche, Mathilde Hauge
Patent no.: NO20071091 , Date: 2007-04-30

Type: Patent

Status: Published     |    Year: 2006

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Nmr-based methods for detecting ligands, where the ligand or target are hyperpolarized and the nmr-spectrum is compared with a reference spectrum of the ligand or target

Ardenkjær-Larsen, Jan Henrik ; Baumann, Herbert (Inventor) ; Cotton Graham, J (Inventor) ; Golman, Klaes (Inventor) ; Howard, Mark (Inventor) ; Lerche, Mathilde Hauge ; Servin, Rolf (Inventor) ; Thanning, Mikkel (Inventor) ; Wolber, Jan (Inventor)
Patent no.: US2006171891, Date: 2003-08-03

Type: Patent

Status: Published     |    Year: 2006

2005
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In vitro method for characterizing the metabolic stability of a hyperpolarized drug candidate

Lerche, Mathilde Hauge ; Golman, Klaes (Inventor)
Patent no.: EP1544634, Date: 2005-06-22

Type: Patent

Status: Published     |    Year: 2005

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Method for characterizing metabolic stability of a drug

Lerche, Mathilde Hauge ; Golman, Klaes (Inventor)
Patent no.: US2005170331, Date: 2005-08-04

Type: Patent

Status: Published     |    Year: 2005

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Method for phenotyping using nmr spectroscopy

Clark, Bill (Inventor) ; Golman, Klaes (Inventor) ; Lerche, Mathilde Hauge ; Looker, Mike (Inventor) ; O'Sullivan, Mike (Inventor) ; Santos, Albie (Inventor) ; Servin, Rolf (Inventor) ; Thanning, Mikkel (Inventor) ; Ardenkjær-Larsen, Jan Henrik
Patent no.: US2005232864, Date: 2005-05-13

Type: Patent

Status: Published     |    Year: 2005

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Methods and compound mixtures for determining protein activity using nmr spectroscopy

Clark, Bill (Inventor) ; Golman, Klaes (Inventor) ; Lerche, Mathilde Hauge ; Looker, Mike (Inventor) ; O'Sullivan, Mike (Inventor) ; Santos, Albie (Inventor) ; Servin, Rolf (Inventor) ; Thanning, Mikkel (Inventor) ; Ardenkjær-Larsen, Jan Henrik
Patent no.: US2005233470, Date: 2005-10-20

Type: Patent

Status: Published     |    Year: 2005

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NMR-based methods for detecting ligands, where the ligand or target are hyperpolarised and the nmr-spectrum is compared with a reference spectrum of the ligand or target

Ardenkjær-Larsen, Jan Henrik ; Baumann, Herbert (Inventor) ; Jogn Cotton, Graham (Inventor) ; Golman, Klaes (Inventor) ; Howard, Mark (Inventor) ; Lerche, Mathilde Hauge ; Servin, Rolf (Inventor) ; Thanning, Mikkel (Inventor) ; Wolber, Jan (Inventor)
Patent no.: EP1579232, Date: 2005-09-28

Type: Patent

Status: Published     |    Year: 2005

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Tungsten particles as x-ray contrast agents

Axelsson, Oskar (Inventor) ; Leunbach, Ib (Inventor) ; Karlsson, Magnus
Patent no.: WO2005051435, Date: 2005-06-09

Type: Patent

Status: Published     |    Year: 2005

2004
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Method and apparatus for producing contrast agents for magnetic resonance imaging

Ardenkjær-Larsen, Jan Henrik ; Axelsson, Oskar (Inventor) ; Jóhannesson, Haukur (Inventor)
Patent no.: WO2004019997 , Date: 2004-03-11

Type: Patent

Status: Published     |    Year: 2004

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Method and apparatus for producing contrast agents for magnetic resonance imaging

Goldman, Maurice (Inventor) ; Axelsson, Oskar (Inventor) ; Jóhannesson, Haukur (Inventor) ; Ardenkjær-Larsen, Jan Henrik
Patent no.: WO2004019995 , Date: 2004-03-11

Type: Patent

Status: Published     |    Year: 2004

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Method and arrangement for producing contrast agent for magnetic resonance imaging

Ardenkjær-Larsen, Jan Henrik ; Axelsson, Oskar (Inventor) ; Goldman, Maurice (Inventor) ; Jóhannesson, Haukur (Inventor)
Patent no.: WO2004019996 , Date:

Type: Patent

Status: Published     |    Year: 2004

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Multidimensional nmr spectroscopy of a hyperpolarized sample

Servin, Rolf (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Jóhannesson, Haukur (Inventor) ; Goldman, Maurice (Inventor) ; Wolber, Jan (Inventor)
Patent no.: WO2004090563, Date: 2004-10-21

Type: Patent

Status: Published     |    Year: 2004

2003
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Mr-method for the in vivo measurement of temperature or ph-value by means of a hyperpolarised contrast agent

Axelsson, Oskar (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Månsson, Sven (Inventor) ; Petersson, Stefan (Inventor) ; Leunbach, Ib (Inventor)
Patent no.: US2003124732, Date: 2003-07-03

Type: Patent

Status: Published     |    Year: 2003

2002
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Methods and devices for dissolving hyperpolarised solid material for nmr analyses

Ardenkjær-Larsen, Jan Henrik ; Axelsson, Oskar (Inventor) ; Golman, Klaes Koppel (Inventor) ; Hansson, Georg (Inventor) ; Jóhannesson, Haukur (Inventor) ; Servin, Rolf (Inventor) ; Thaning, Mikkel (Inventor) ; Hansson, Lennart (Inventor)
Patent no.: WO0237132 , Date: 2002-05-10

Type: Patent

Status: Published     |    Year: 2002

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Methods of magnetic resonance imaging (MRI) using contract agent solutions formed from the dissolution of hyperpolarised materials

Axelsson, Oskar (Inventor) ; Johannesson, Haukur (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Laursen, Ib (Inventor)
Patent no.: GB2364785, Date: 2002-02-06

Type: Patent

Status: Published     |    Year: 2002

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Process for preparation of MR contrast agents

Axelsson, Oskar (Inventor) ; Olofsson, Charlotte (Inventor) ; Morgenstjerne, Axel ; Hansson, Georg (Inventor) ; Johannesson, Haukur (Inventor) ; Ardenkjær-Larsen, Jan Henrik
Patent no.: US2002137965, Date: 2002-09-26

Type: Patent

Status: Published     |    Year: 2002

2001
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Method for investigating the fate of a test compound or the stateof a biological system by means of nmr of hyperpolarised nmr active nuclei.

Cook, Neil (Inventor) ; Santos, Albie (Inventor) ; Bosworth, Nigel (Inventor) ; Wolber, Jan (Inventor) ; Looker, Mike (Inventor) ; Knox, Peter (Inventor) ; Ardenkjær-Larsen, Jan Henrik ; Golman, Klaes (Inventor)
Patent no.: WO0196895, Date: 2001-01-20

Type: Patent

Status: Published     |    Year: 2001

2000
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NMR spectroscopic in vitro assay using hyperpolarization

Knox, Peter (Inventor) ; Cook, Neil (Inventor) ; Golman, Klaes (Inventor) ; Johanneson, Haukur (Inventor) ; Axelsson, Oksar (Inventor) ; Ardenkjær-Larsen, Jan Henrik
Patent no.: WO0040988, Date: 2000-07-13

Type: Patent

Status: Published     |    Year: 2000

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Overhauser enhanced magnetic resonance imaging technique (OMRI or PEDRI or ESREMRI)

Ardenkjær-Larsen, Jan Henrik
Patent no.: US6108574, Date: 2000-08-22

Type: Patent

Status: Published     |    Year: 2000

1999
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Method of magnetic resonance investigation

Ardenkjær-Larsen, Jan Henrik ; Axelsson, Oskar (Inventor) ; Golman, Klaes (Inventor) ; Wistrand, Lars-Göran (Inventor) ; Hansson, Georg (Inventor) ; Leunbach, Ib (Inventor) ; Petersson, Stefan (Inventor)
Patent no.: WO9935508 , Date: 1999-07-15

Type: Patent

Status: Published     |    Year: 1999

1998
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Overhauser magnetic resonance imaging (ormi) method comprising ex vivo polarization of a magnetic resonance (mr) imaging agent.

Ardenkjær-Larsen, Jan Henrik ; Golman, Klaes (Inventor) ; Hansson, Georg (Inventor) ; Leunbach, Ib (Inventor) ; Petersson, Stefan (Inventor) ; Wistrand, Lars-Goran (Inventor) ; Axelsson, Oskar (Inventor)
Patent no.: WO9858272, Date: 1998-12-23

Type: Patent

Status: Published     |    Year: 1998

1997
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A method for determining the oxygen concentration of a sample.

Ardenkjær-Larsen, Jan Henrik ; Leunbach, Ib (Inventor)
Patent no.: WO9709633, Date: 1997-03-13

Type: Patent

Status: Published     |    Year: 1997

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ESR-enhanced MRI using magnetic particles as contrast agents

Ardenkjær-Larsen, Jan Henrik ; Laursen, Ib (Inventor) ; Leunbach, Ib (Inventor) ; Golman, Klaes (Inventor)
Patent no.: GB2311138, Date: 1997-09-17

Type: Patent

Status: Published     |    Year: 1997

1995
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Method and apparatus for measuring weak magnetic fields.

Ardenkjær-Larsen, Jan Henrik
Patent no.: WO9517684, Date: 1995-06-29

Type: Patent

Status: Published     |    Year: 1995