Hyperpolarization via dissolution Dynamic Nuclear Polarization is a highly promising novel technology that has the potential to unravel disease and promote novel treatment regimes by virtue of enabling real-time metabolic studies.
Saket will be working on a recent idea of generating long-lasting transportable hyperpolarized metabolites for Magnetic Resonance via photo-induced persistent radical species. The value proposition of UV-generated radicals is two-fold: it may solve the inherent challenge for hyperpolarization that is the very short nuclear relaxation time; and it may make hyperpolarization more accessible to hospitals and research institutions lacking a polarizer on site.
Saket's long-term aims are to understand the photo-chemistry of the optically induced radical species and to demonstrate the feasibility of the method in investigating specific organ metabolism through pre-clinical and clinical studies. He is employed for the period March - August 2019.
Saket holds an MSc degree from Institute of Science, Education and Research Bhopal, India, in organic chemistry, and a PhD degree in dissolution Dynamic Nuclear Polarization from Aix Marseille University.